PCNA Monoclonal Antibody (12D10) - BT-MCA0068

PCNA Monoclonal Antibody (12D10)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0068-20, BT-MCA0068-50, BT-MCA0068-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Research Areas: Cancer; Cell biology; Epigenetics and nuclear signaling; Tags and; cell markers

Target Protein: PCNA

Applications: WB, IF, ICC, IHC-p

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Proliferating cell nuclear antigen

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 28769

UniProt Accession: Human: P12004; Mouse: P17918; Rat: P04961

Synonyms: PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin

GeneID: Human: 5111; Mouse: 18538; Rat: 25737

Research Use Only