Product Description

PCNA Monoclonal Antibody (12D10), HRP Conjugated

Sizes: 50μL, 100μL

Catalogue Numbers: RA11821-50, RA11821-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: proliferating cell nuclear antigen (PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: WB, IF/ICC, IHC-p

Alternate Names: PCNA

Clonality: Monoclonal

Dilution: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:5000, IHC: 1:200.

Storage: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Condition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.

Human Gene ID: 5111

Research Use Only