PCNA Monoclonal Antibody (12D10) - RA10511

PCNA Monoclonal Antibody (12D10)

Size: 50μL, 100μL

Catalogue Numbers: RA10511-50, RA10511-100

Citations, Manuals and MSDS Available upon request.

Background: proliferating cell nuclear antigen (PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IF/ICC; IHC-p

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5111

Protein MW (KDa): 29

SWISS: P12004

Source: Mouse

Research Use Only