Product Description

PCP4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65683-50, BS65683-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: PCP-4 is a calmodμlin (CaM) regμlatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer’s disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Cow, Sheep

Host: Rabbit

Applications: IHC-P

Alternate Names: Brain specific antigen PCP 4, Brain specific polypeptide PEP 19, Brain specific polypeptide PEP19, PEP19, Purkinje cell protein 4, PCP-4, PCP4_HUMAN, PEP-19.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PCP4

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: PCP4 Polyclonal Antibody detects endogenous levels of PCP4 protein.

Molecular Weight: 7kD

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P48539

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only