Product Description

PCSK9 Mouse Monoclonal Antibody (5G4)

Sizes: 50μL, 100μL

Catalogue Numbers: RA11824-50, RA11824-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: proprotein convertase subtilisin/kexin type 9 (PCSK9) Homo sapiens This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: IHC-p, WB

Alternate Names: Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9)

Clonality: Monoclonal

Dilution: IHC-p1:50-200, WB 1:1000-2000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.84% sodium azide.

Human Gene ID: 255738

Protein Molecular Weight（KDa): 74

Molecular Weight: 74

Research Use Only