Product Description

PD-L2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28645-50, RA28645-100

Citations, Manuals and MSDS Available upon request.

Background: function:Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.,induction:Up-regulated by IFNG stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4.,similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with PDCD1.,tissue specificity:Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000,IHC-p 1:50-200, ELISA 1:10000-20000

Alternative Names: Programmed cell death 1 ligand 2 (PD-1 ligand 2;PD-L2;PDCD1 ligand 2;Programmed death ligand 2;Butyrophilin B7-DC;B7-DC;CD antigen CD273)

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 80380

Protein MW (KDa): 30

SWISS: Q9BQ51

Source: Rabbit

Research Use Only