Pdcd-1 rabbit pAb - ES20278

Pdcd-1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20278-50, ES20278-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],

Alternate Name: Programmed cell death protein 1 (Protein PD-1; hPD-1; CD antigen CD279)

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human Pdcd-1 AA range: 80-130

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 5133

Human SWISS Prot NO: Q15116

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only