Product Description

PDE10A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06998-20, BT-AP06998-50, BT-AP06998-100

Citations, Manuals and MSDS Available upon request.

Background: The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for PDE10A.

Research Areas: Signal Transduction

Target Protein: PDE10A

Applications: WB, ELISA

Reactivity: Human, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PDE10A Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 88412

UniProt Accession: Human: Q9Y233; Mouse: Q8CA95; Rat: Q9QYJ6

Synonyms: PDE10A; cAMP and cAMP-inhibited cGMP 3'; 5'-cyclic phosphodiesterase 10A

GeneID: Human: 10846; Rat: 63885

Research Use Only