PDE4C Polyclonal Antibody-BS75141

PDE4C Polyclonal Antibody

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS75141-50, BS75141-100

Swiss-Prot: Q08493

Host: Rabbit

Reactivity: Human, Rat

Applications: IF/ICC

All Applications: IF/ICC,1:50 - 1:400

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of PC-12 cells using PDE4C antibody at dilution of 1:400.Blue: DAPI for nuclear staining.

Alternative Name: PDE4C; DPDE1; PDE21

Immunogen: Recombinant fusion protein of human PDE4C (NP_000914.2).

Conjugate: Unconjugated

Modification: Unmodified