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PDE6D Polyclonal Antibody - E-AB-65101

PDE6D Polyclonal Antibody - E-AB-65101

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PDE6D Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-65101-60, E-AB-65101-120, E-AB-65101-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PDE6D

Target Synonym: PDE6D; JBTS22; PDED

Research Areas: Cancer, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O43924

Background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PDE6D (NP_002592.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only