PDE6G Rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES14185-50, ES14185-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
Alternate Name: Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma; EC 3.1.4.35)
Source: Rabbit
Applications: IHC; ELISA
Dilution: IHC-p 1:50-200, ELISA (peptide)1:5000-20000
Reactivity: Human; Mouse
Immunogen: Synthesized peptide derived from human PDE6G AA range: 10-90
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human Gene ID: 5148
Human SWISS Prot NO: P18545
Subcellular Location: plasma membrane, photoreceptor disc membrane,
Research Use Only