PDE7A Polyclonal Antibody - BT-AP12877

PDE7A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12877-20, BT-AP12877-50, BT-AP12877-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research Areas: Neuroscience; Signal transduction

Target Protein: PDE7A

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13946; Mouse: P70453; Rat: O08593

Synonyms: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A;EC 3.1.4.17;HCP1;TM22

GeneID: Human: 5150

Research Use Only