PDGFRα Mouse Monoclonal Antibody (7A3) - RA11827

PDGFRα Mouse Monoclonal Antibody (7A3)

Size: 50μL, 100μL

Catalogue Numbers: RA11827-50, RA11827-100

Citations, Manuals and MSDS Available upon request.

Background: platelet derived growth factor receptor alpha (PDGFRA) Homo sapiens This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IF/ICC; IHC-p

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5156

Protein MW (KDa): 180

SWISS: P16234

Source: Mouse

Research Use Only