PDGFRα Mouse Monoclonal Antibody (7A3)
Sizes: 50μL, 100μL
Catalogue Number: RA11827-50, RA11827-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store At/In: -20°C/1 year
Recommended Dilutions: IF: 1:50-200 IHC 1:100-200
Alternative Names: PDGFRA
Background: platelet derived growth factor receptor alpha(PDGFRA) Homo sapiens This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012],
Applications: IF/ICC; IHC-p
Species Cross-Reactivity: Human; Rat; Mouse
Molecular Weight: 180
GeneID (Human): 5156
Protein MW (KDa): 180
SWISS: P16234
Source: Mouse
Research Use Only