PDGFRA Monoclonal Antibody - BT-MCA3810

PDGFRA Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3810-50, BT-MCA3810-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Research Areas: Cardiovascular

Target Protein: PDGFRA

Applications: ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8E12F2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PDGFRA

Immunogen: Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 122.7kDa

UniProt Accession: P16234

Synonyms: CD140A, PDGFR2, PDGFR-2, RHEPDGFRA

GeneID: 5156

Research Use Only