PDGFRAlpha mouse Monoclonal Antibody (4G11) - BT-MCA1010

PDGFRAlpha mouse Monoclonal Antibody (4G11)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA1010-20, BT-MCA1010-50, BT-MCA1010-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Research Areas: Signal transduction; Cancer; Cardiovascular

Target Protein: PDGFRA

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: PDGFRA

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P16234; Mouse: P26618; Rat: P20786

Synonyms: PDGFRA

GeneID: Human: 5156

Research Use Only