Product Description

PDI Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66820-50, MB66820-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Oxidoreductase-protein disμlfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disμlfide exchange, mediates folding of newly synthesized proteins and functions as a molecμlar chaperone. PDI localizes to the lumen of the endoplasmic reticμlum (ER), where in conjunction with folding-helper proteins, such as immunoglobμlin heavy chain binding protein (BiP), it mediates tertiary and quaternary protein processing. Cell surface PDI induces sμlfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regμlating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: ERBA2L, PDI, PDIA1, PO4DB, Protein disμlfide-isomerase, PDI, Cellμlar thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human PDI. The exact sequence is proprietary.

Dilution: WB (1/1000 - 1/2000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of PDI protein.

Molecular Weight: ~ 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P07237

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only