PDK1 (Phospho Tyr243) rabbit pAb - ES20214

PDK1 (Phospho Tyr243) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20214-50, ES20214-100

Citations, Manuals and MSDS Available upon request.

Background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],

Alternate Name: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial (EC 2.7.11.2; Pyruvate dehydrogenase kinase isoform 1)

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human PDHK1 (Phospho Tyr243)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 50kD

Human Gene ID: 5163

Human SWISS Prot NO: Q15118

Subcellular Location: Mitochondrion matrix.

Research Use Only