PDK2 Polyclonal Antibody - BT-AP07031

PDK2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07031-20, BT-AP07031-50, BT-AP07031-100

Citations, Manuals and MSDS Available upon request.

Background: PDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

Research Areas: Signal Transduction; Metabolism

Target Protein: PDK2

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PDK2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 46154

UniProt Accession: Human: Q15119; Mouse: Q9JK42; Rat: Q64536

Synonyms: PDK2; PDHK2; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2; mitochondrial; Pyruvate dehydrogenase kinase isoform 2

GeneID: Human: 5164; Mouse: 18604; Rat: 81530

Research Use Only