PDLIM5 (phospho Tyr251) rabbit pAb - ES4519

PDLIM5 (phospho Tyr251) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4519-50, ES4519-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],

Alternate Name: PDLIM5; ENH; L9; PDZ and LIM domain protein 5; Enigma homolog; Enigma-like PDZ and LIM domains protein

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human PDLIM5 (phospho Tyr251)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 64kD

Human Gene ID: 10611

Human SWISS Prot NO: Q96HC4

Subcellular Location: Cell junction, synapse, postsynaptic density. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse. Cytoplasm, cytosol. Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons.

Research Use Only