PDX1 Monoclonal Antibody - BT-MCA2456

PDX1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2456-50, BT-MCA2456-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Research Areas: Signal Transduction

Target Protein: PDX1

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2G12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PDX1

Immunogen: Purified recombinant fragment of human PDX1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 30.8kDa

UniProt Accession: P52945

Synonyms: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1

GeneID: 3651

Research Use Only