Product Description

PDX1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91049-50, BS91049-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P52945(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, ICC/IF

All Applications: IHC:1:50-1:200
ICC/IF:1:50-1:200
WB:1:500

Background: Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: PDX1 polyclonal antibody detects endogenous levels of PDX1 protein.

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody. Counter stained with hematoxylin., IF analysis of paraffin-embedded human pancreas tissue using anti-PDX1 antibody (green）. The nuclear counter stain is DAPI (blue).