PDZ-RhoGEF Polyclonal Antibody - BT-AP07043

PDZ-RhoGEF Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07043-20, BT-AP07043-50, BT-AP07043-100

Citations, Manuals and MSDS Available upon request.

Background: Periphilin 1 encoded by PPHLN1 is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. Periphilin 1 interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of periphilin 1 suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Research Areas: Signal Transduction

Target Protein: ARHGEF11

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PDZ-RhoGEF Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 167704

UniProt Accession: Human: O15085; Rat: Q9ES67

Synonyms: ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF

GeneID: Human: 9826; Rat: 78966

Research Use Only