PDZ-RhoGEF rabbit pAb - ES3173

PDZ-RhoGEF rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3173-50, ES3173-100

Citations, Manuals and MSDS Available upon request.

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Alternate Name: ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 9826

Human SWISS Prot NO: O15085

Subcellular Location: Cytoplasm. Membrane. Translocated to the membrane upon stimulation.

Research Use Only