PE-Cy5 Anti-Rat CD45 Antibody (OX-1)
Sizes: 25μg, 100μg
Catalogue Numbers: PC5-30009U-25, PC5-30009U-100
Citations, Manuals and MSDS Available upon request.
Target: Rat CD45
Form: Liquid
Conjugation: PE-Cy5
Conjugation Information: PE-Cy5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: OX-1
Isotype: IgG1, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 Antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.
Synonyms: LCALy-5T200| Leukocyte common antigen| Ptprc| Receptor-type tyrosine-protein phosphatase C
Uniprot ID: P04157
Reactivity: Rat
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 19265
Category: Flow cytometryometry Antibodies
Research Use Only