PE-Cy7 Anti-Human CD32 Antibody (IV-3)
Sizes: 20T, 100T
Catalogue Numbers: PC7-30241-20, PC7-30241-100
Citations, Manuals and MSDS Available upon request.
Target: Human CD32
Form: Liquid
Conjugation: PE-Cy7
Conjugation Information: PE-Cy7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: IV-3
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
Synonyms: IGFR2|CD32|CDw32|FCG2|FCGR2B|Fc-gamma RII-b|Fc-gamma-RIIb|FcRII-b|IgG Fc receptor II-b|Low affinity immunoglobulin gamma Fc region receptor II-b
Uniprot ID: P31994
Reactivity: Human
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 2212
Category: Flow cytometryometry Antibodies
Research Use Only