PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7] - E-AB-F1100UG

PE/Cyanine5 Anti-Human/Mouse CD44 Antibody [IM7]

Size: 100μg

Catalogue Number: E-AB-F1100UG-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD44

Target Synonym: CD44 antigen, CD44, CDw44, Epican, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, LHR, MDU2, MDU3, MIC4,

Conjugation: PE/Cyanine5

Host: Rat

Species Reactivity: Human, Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2b, κ

Clone No.: IM7

UNIProt ID: P15379, P16070,

Background: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09843G

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 12, 505, 960

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag