Product Description

PE Mouse Anti-Human CD28 Monoclonal Antibody

Sizes: 25 tests, 100μl

Catalogue Numbers: MB8503P-25, MB8503P-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD28 is one of the proteins expressed on T cells that provide co-stimμlatory signals required for T cell activation and survival. T cell stimμlation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particμlar). CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregμlated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive (expression is independent of environmental factors).CD28 is the only B7 receptor constitutively expressed on naive T cells. Association of the TCR of a naive T cell with MHC:antigen complex without CD28:B7 interaction resμlts in a T cell that is anergic.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: FC

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Dilution: FC:5μl per test

Purification: Protein A affinity purified

Specificity: This antibody detects Extracellμlar domain of human CD28.

Storage and Stability: Store at 4°C . Avoid freezed.

SwissProt: P10747

Product: Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only