PE Rabbit anti-Human Phospho-Histone H2AX-S139 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: AP1529-100, AP1529-200, AP1529-500
Citations, Manuals and MSDS Available upon request.
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
Category: Phosphorylated Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 15kDa Immunogen: Synthetic peptide.
Species: Human
GeneID: 3014
SWISS: P16104
Alternate Names: H2A.X; H2A/X; H2AFX
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, Protein phosphorylation, ATM Signaling Pathway
NCBI Alias: H2AX
Modifications: Unmodified
Conjugate: PE. Ex:565nm. Em:574nm.
Clone Number Info: ARC70320
Research Use Only