PE Rabbit anti-Human TIM-3/HAVCR2 Monoclonal Antibody - A27986

PE Rabbit anti-Human TIM-3/HAVCR2 Monoclonal Antibody

Sizes: 100T, 2 x 100T, 5 x 100T

Catalogue Numbers: A27986-100, A27986-200, A27986-500

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Category: Monoclonal Antibodies

Application: FC

Cross Reactivity: Human

Protein Weight: 33kDa Immunogen: Recombinant protein (or fragment).

Species: Human

GeneID: 84868

SWISS: Q8TDQ0

Alternate Names: TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.

Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume

Research Areas: Immunology Inflammation, Cell Intrinsic Innate Immunity Signaling Pathway

NCBI Alias: HAVCR2

Modifications: Unmodified

Conjugate: PE. Ex:565nm. Em:574nm.

Clone Number Info: ARC54204

Research Use Only