Product Description

PEG10 Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11835-50, RA11835-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: paternally expressed 10 (PEG10) Homo sapiens This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis.

Reactivity: Human

Host: Mouse

Applications: WB, IP

Alternate Names: AA407948, Edr, Embryonal carcinoma differentiation regulated, Embryonal carcinoma differentiation-regulated protein, HB 1, HB1, KIAA1051, Mammalian retrotransposon-derived protein 2, Mar2, Mart2, MEF3 like 1, MEF3-like protein 1, MEF3L, MEF3L1, MyEF 3, Myelin expression factor 3-like protein 1, Paternally expressed 10, Paternally expressed gene 10 ORF1, Paternally expressed gene 10 protein, Peg10, PEG10 protein, PEG10_HUMAN, Putative uncharacterized protein PEG10, Retrotransposon gag domain containing 3, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Retrotransposon-derived protein PEG10, RGAG3, Ty3/Gypsy-like protein.

Clonality: Monoclonal

Dilution: wb 1:1000

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 23089

Protein Molecular Weight（KDa): 55

Molecular Weight: 55

Research Use Only