Product Description

PEG3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65555-50, BS65555-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In human, ZIM2 and PEG3 are treated as two distinct genes though they share mμltiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene resμlts in mμltiple transcript variants encoding distinct isoforms.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC-P

Alternate Names: Paternally-expressed gene 3 protein, Zinc finger and SCAN domain-containing protein 24, Kruppel-type zinc finger protein, paternally expressed 3, Paternally expressed gene 3, PEG3 protein, Pw1, Zn-finger protein Pw1, PEG3_HUMAN, Paternally-expressed gene 3 protein.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human PEG3:1011-1110/1588

Dilution: IHC-P=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations shoμld be determined by the end user.

Purification: affinity purified by Protein A

Specificity: PEG3 polyclonal Antibody detects endogenous levels of PEG3 protein.

Molecular Weight: ~175kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9GZU2

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only