PEG3 rabbit pAb - ES6567

PEG3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6567-50, ES6567-100

Citations, Manuals and MSDS Available upon request.

Background: In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009],

Alternate Name: PEG3; KIAA0287; ZSCAN24; Paternally-expressed gene 3 protein; Zinc finger and SCAN domain-containing protein 24

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human PEG3. AA range:1031-1080

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 181kD

Human Gene ID: 5178

Human SWISS Prot NO: Q9GZU2

Subcellular Location: Nucleus. Cytoplasm.

Research Use Only