Product Description

PENK Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66762-50, MB66762-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The corticotropin-lipotropin protein, also designated pro-opiomelanocortin, belongs to the POMC family of proteins. Specific cleavages by enzymes at certain basic paired residues yield various processed active peptides. The corticotropin-lipotropin protein contains synenkephalin, Leu-enkephalin, NPP, a-, b- and g-melanotropin (MSH), adrenocorticotropic hormone (ACTH), lipotropin b and g, b-endorphin and Met-enkephalin processed active peptides.b-endorphin and Met-enkephalin are endogenous opiates while ACTH is crucial for adrenal gland stimμlation to release cortisol. Met/Leu-enkephalins also function in pain perception and response to stress. MSH increased melanin production in melanocytes which leads to an increase in skin pigmentation. Leumorphin may be important in apoptosis prevention by being involved in the MAP-K and PI3-K pathways.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: Proenkephalin-A

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human PENK. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of PENK protein.

Molecular Weight: ~ 34 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01210

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only