Product Description

PENK Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8113-50, BS8113-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The Proenkephalin precursor proteins are secreted proteins belonging to the opioid neuropeptide precursor family. The proenkephalin proteins are proteolytically processed to form active secreted opioid peptides which function as ligands for the κ-type of opiod receptor. Proenkephalin A precursor contains Synenkephalin, Leu-enkephalin and Met-enkephalin processed active peptides while the Proenkephalin B precursor contains β-neoendorphin, Dynorphin, Leumorphin, Leu-enkephalin and Rimorphin processed active peptides. β-endorphin and Met-enkephalin are endogenous opiates while ACTH is crucial for adrenal gland stimμlation to release cortisol. MSH increases Melanin production in melanocytes which leads to an increase in skin pigmentation. Leumorphin may be important in apoptosis prevention by being involved in the MAP-K and PI 3-K pathways.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Proenkephalin-A, PENK

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human PENK.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PENK polyclonal antibody detects endogenous levels of PENK protein.

Molecular Weight: ~ 36 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01210

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only