Product Description

PEPC Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA30857-50, RA30857-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: progastricsin (PGC) Homo sapiens This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],

Reactivity: Plants

Host: Rabbit

Applications: WB

Alternate Names: PGC, Gastricsin, Pepsinogen C, YM3346

Clonality: Polyclonal

Dilution: WB: 1:2000-5000

Molecular Weight: 105-109

Protein Molecular Weight (kDa): 105-109

Storage: -20°C/1 year

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Research Use Only