Product Description

Pepsin A Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28675-50, RA28675-100

Citations, Manuals and MSDS Available upon request.

Background: pepsinogen 5, group I (pepsinogen A) (PGA5) Homo sapiens This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: Pepsin A; PGA3; PGA4; PGA5

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5222/643847

Protein MW (KDa): 42

SWISS: P00790

Source: Rabbit

Research Use Only