Per3 Polyclonal Antibody - BT-AP07062

Per3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07062-20, BT-AP07062-50, BT-AP07062-100

Citations, Manuals and MSDS Available upon request.

Background: PER3 (period circadian clock 3) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER3 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER3 have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for PER3.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: PER3

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Per3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 131872/43102

UniProt Accession: Human: P56645; Mouse: O70361

Synonyms: PER3; GIG13; Period circadian protein homolog 3; hPER3; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3

GeneID: Human: 8863

Research Use Only