PerCP-Cy5.5 Anti-Human CD107a Antibody (H4A3)
Sizes: 20T, 100T
Catalogue Numbers: PCP55-30046-20, PCP55-30046-100
Citations, Manuals and MSDS Available upon request.
Target: Human CD107a/LAMP
Form: Liquid
Conjugation: PerCP-Cy5.5
Conjugation Information: PerCP-Cy5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: H4A3
Isotype: IgG1, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Synonyms: LAMP-1LGP-120|Lysosome-Associated Membrane Protein 1|LAMP-1
Uniprot ID: P11279
Reactivity: Human
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 3916
Category: Flow cytometryometry Antibodies
Research Use Only