PerCP/Cyanine5.5 Rabbit anti-Human/Monkey PD-1/CD279 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: A28238-100, A28238-200, A28238-500
Citations, Manuals and MSDS Available upon request.
Background: Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Category: Monoclonal Antibodies
Application: FC
Cross Reactivity: Human, Cynomolgus
Protein Weight: 32 kDa Immunogen: Recombinant protein (or fragment).
Species: Human
GeneID: 5133
SWISS: Q15116
Alternate Names: PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.
Recommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume
Research Areas: Cell Biology Developmental Biology, Apoptosis, Immunology Inflammation, CDs
NCBI Alias: PDCD1
Modifications: Unmodified
Conjugate: PerCP-Cy5.5. Ex:482nm. Em:695nm.
Clone Number Info: ARC64145
Research Use Only