Product Description

Perforin 1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28680-50, RA28680-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: perforin 1 (PRF1) Homo sapiens The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC, ELISA

Alternate Names: Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)

Clonality: Polyclonal

Dilution: WB 1:500-2000, IHC 1:50-200, ELISA 1:10000-20000

Molecular Weight: 61

Protein Molecular Weight (kDa): 61

Storage: -20°C/1 year

Human Gene ID: 5551

Human SwissProt Number: P14222

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only