PERM (light chain, Cleaved-Gly278) rabbit pAb - ES20033

PERM (light chain, Cleaved-Gly278) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20033-50, ES20033-100

Citations, Manuals and MSDS Available upon request.

Background: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014],

Alternate Name: Myeloperoxidase (MPO; EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human PERM (light chain, Cleaved-Gly278)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 12 84 89kD

Human Gene ID: 4353

Human SWISS Prot NO: P05164

Subcellular Location: Lysosome.

Research Use Only