Product Description

Peroxin 5 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28694-50, RA28694-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: peroxisomal biogenesis factor 5 (PEX5) Homo sapiens The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD)

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: PEX5, PXR1, Peroxisomal targeting signal 1 receptor, PTS1 receptor, PTS1R, PTS1-BP, Peroxin-5, Peroxisomal C-terminal targeting signal import receptor, Peroxisome receptor 1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 70

Protein Molecular Weight (kDa): 70

Storage: -20°C/1 year

Human Gene ID: 5830

Human SwissProt Number: P50542

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only