Product Description

PFK-2 car Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28702-50, RA28702-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2 (PFKFB2) Homo sapiens The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2, 6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2, 6-bisphosphate, and a fructose-2, 6-biphosphatase activity that catalyzes the degradation of fructose-2, 6-bisphosphate. This protein regulates fructose-2, 6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2, 6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC-p, IF (paraffin section), ELISA

Alternate Names: PFKFB2, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2, 6PF-2-K/Fru-2, 6-P2ase 2, PFK/FBPase 2, 6PF-2-K/Fru-2, 6-P2ase heart-type isozyme

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Molecular Weight: 58

Protein Molecular Weight (kDa): 58

Storage: -20°C/1 year

Human Gene ID: 5208

Human SwissProt Number: O60825

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only