PFK-2 liv rabbit pAb - ES3183

PFK-2 liv rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3183-50, ES3183-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2, 6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2, 6-biphosphate using independent catalytic domains. Fructose-2, 6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2, 6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012],

Alternate Name: PFKFB1; F6PK; PFRX; 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2, 6-P2ase 1; PFK/FBPase 1; 6PF-2-K/Fru-2, 6-P2ase liver isozyme

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PFKFB1. AA range:406-455

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 58kD

Human Gene ID: 5207

Human SWISS Prot NO: P16118

Subcellular Location: cytosol, 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase complex,

Research Use Only