PGAM1 Polyclonal Antibody-BS91061

PGAM1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91061-50, BS91061-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P18669(Human) Q9DBJ1(Mouse) P25113(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB:1:500-1:2,000
IHC:1:50-1:100
FC:1:50-1:100

Background: Members of the PGAM (phosphoglycerate mutase) family of proteins are important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism. They are responsible for catalyzing the transfer of phospho groups between the carbon atoms of phosphoglycerates. In mammals there are two types of PGAM isozymes: PGAM1 (also known as PGAMB) and PGAM2 (also known as PGAMA). In the cell, PGAM1 and PGAM2 exist as either homodimers or heterodimers and are responsible for the interconversion of 3-phosphoglycerate and 2-phosphoglycerate. PGAM2 homodimers are expressed in skeletal muscle, mature sperm cells and heart; PGAM1 homodimers are found in most other tissues; and PGAM1/PGAM2 heterodimers are found exclusively in the heart. PGAM4, also known as PGAM3, is a protein formerly considered to be specific to humans. Initially the PGAM4 gene was described as a pseudogene but it is now known to encode a functional protein at least 25 million years old. The gene encoding PGAM4 is believed to have originated by retrotransposition, with the original copy being the PGAM1 gene.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: PGAM1 polyclonal antibody detects endogenous levels of PGAM1 protein.

Bioworld Molecular Weight: 29 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PGAM1 on different lysates using anti-PGAM1 antibody at 1/2,000 dilution.
Positive control:
Lane 1: A431
Lane 2: A549
Lane 3: Rat brain
Lane 4: Mouse brain, Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-PGAM1 antibody. Counter stained with hematoxylin.

Alternative Name: PGAM-B, PGAM1, PGAMA, BPG dependent PGAM 1, BPG dependent PGAM1, BPG-dependent PGAM 1, OTTHUMP00000059414, PGAM 1, PGAM A, PGAM B, PGAM-B, PGAM1, PGAM1, PGAMA, PGAMB, Phosphoglycerate mutase 1, Phosphoglycerate mutase 1 brain, Phosphoglycerate mutase A, Phosphoglycerate mutase A nonmuscle form, Phosphoglycerate mutase isozyme B,

Conjugate: Unconjugated

Modification: Unmodified