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PGAM5 Polyclonal Antibody - E-AB-91403

PGAM5 Polyclonal Antibody - E-AB-91403

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PGAM5 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-91403-60, E-AB-91403-120, E-AB-91403-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PGAM5

Target Synonym: PGAM5; BXLBV68

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96HS1

Background: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PGAM5

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200

Calculated MW: 28kDa/32kDa

Observed MW: 28KDa/30KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only