PGC-1α Monoclonal Antibody - RA11840

PGC-1α Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11840-50, RA11840-100

Citations, Manuals and MSDS Available upon request.

Background: PPARG coactivator 1 alpha (PPARGC1A) Homo sapiens The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs) . It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 10891

SWISS: Q9UBK2

Source: Mouse

Research Use Only