Product Description

PGC1β Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91063-50, BS91063-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q86YN6(Human) Q8VHJ7(Mouse) Q811R2(Rat)

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IP, FC

All Applications: WB:1:500-1:2,000
FC:1:50-1:200
IP:1:10-1:50

Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: PGC1β polyclonal antibody detects endogenous levels of PGC1β protein.

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PGC1 beta on rat spleen tissue lysate using anti-PGC1 beta antibody at 1/1,000 dilution., Flow cytometric analysis of HL-60 cells with PGC1 beta antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).