PGE synthase (I79) Polyclonal Antibody-BS2846

PGE synthase (I79) Polyclonal Antibody

Catalogue Numbers: BS2846-50, BS2846-100

Sizes: 50µl, 100µl

Alternative Name: Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; Short name=MGST1-L1; Microsomal prostaglandin E synthase 1; Short name=MPGES-1; p53-induced gene 12 protein; PTGES; MGST1L1; MPGES1; PGES; PIG12

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O14684

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Prostaglandin E synthase (PGE synthase), also known as PIG12 and MGST1-L1, is a member of protein super family MAPEG, which consists of membrane associated proteins involved in eicosanoid and glutathione metabolism. The expression of this membrane-associated protein can be induced by the pro-inflammatory cytokine, IL-1β. PGE synthase is expressed in seminal vesicles, deferent ducts, kidney, heart and spleen. The enzyme activity of PGE synthase in most organs is glutathione-dependent. PGE synthase may play a significant role in the progression of Alzheimer’s disease.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PGE synthase (I79) polyclonal antibody detects endogenous levels of PGE synthase protein.

Bioworld Molecular Weight: ~17 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of PGE synthase (I79) polyclonal antibody at 1:500 dilution
Lane 1: NIH-3T3 whole cell lysate(40ug)
Lane 2: Hela whole cell lysate(40ug)
Lane 3: H9C2 whole cell lysate(40ug)
Lane 4: SP2/0 whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 51-100 of Human PGE synthase.

Conjugate: Unconjugated

Modification: Unmodified